Clinical Trials for ZOLINZA
 
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ZOLINZA® (vorinostat) capsules. Get the most from your treatment by learning more about ZOLINZA,
a CTCL medication.
Download and print the Zolinza Patient Brochure to learn more about treatment with ZOLINZA.
Merck
To report side effects, call 800-FDA-1088.
What is ZOLINZA?: Photos of skin improvements

Patients who took part in a study (clinical trial) of ZOLINZA had their skin symptoms evaluated* by doctors before and during treatment. On average, 30% (22 out of 74 patients) saw their skin symptoms improve by 50% or more for at least 4 weeks. The photographs below represent a range of responses that were seen among those people who had skin improvements while taking ZOLINZA. Individual results may vary.

Mycosis Fungoides (Hands) Stage IVA
Before ZOLINZA
Before ZOLINZA
21 weeks later
21 weeks later
37 weeks later
37 weeks later
Mycosis Fungoides (Arm) Stage IIB
Before ZOLINZA
Before ZOLINZA
5 weeks later
5 weeks later
25 weeks later
25 weeks later
Sézary Syndrome (Feet) Stage IVA
Before ZOLINZA
Before ZOLINZA
17 weeks later
17 weeks later
38 weeks later
38 weeks later
*
A severity-weighted assessment tool (SWAT) score was given based on how much of the body showed skin symptoms and how severe the symptoms were. A patient was considered to have responded if his or her SWAT score decreased by 50% or more for at least 4 weeks.

 

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Important information about ZOLINZA

ZOLINZA is a medicine used to treat a type of cancer called cutaneous T-cell lymphoma, also called CTCL. ZOLINZA is used in patients when the CTCL gets worse, does not go away, or comes back after treatment with other medicines.

  • A possible serious side effect is an abnormality on your electrocardiogram, or EKG. Your doctor will check your blood electrolytes and EKG.
  • The most common side effects of ZOLINZA include stomach problems, such as diarrhea, nausea, vomiting, loss of appetite, constipation, and weight loss; tiredness; taste changes; muscle aches; and hair loss.
  • Your doctor will tell you how many ZOLINZA capsules to take and when to take them. Swallow each capsule whole; do not chew it or break it open. If you cannot swallow the capsules whole, tell your doctor. You may need a different medicine.
  • ZOLINZA is available by prescription only.
  • Please read the Patient Information for ZOLINZA and discuss it with your doctor. The physician Prescribing Information also is included on this site.
  • You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
ZOLINZA is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
This site is intended for residents of the United States, its territories, and Puerto Rico.
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