Time to Progression

Half of All Patients (37/74) Had Not Met Progression Criteria at Time of Analysis

• Time to progression was measured from the time treatment began to the time the criteria for progression were first met.
• When tumor progression was defined as a ≥25% increase in SWAT score from baseline, the estimated median time to progression in the overall patient population was 148 days (range: 1–470+ days).
• When tumor progression was defined as a ≥25% increase in SWAT score from the nadir, the estimated median time to progression in the overall patient population was 148 days (range: 1–380 days).

Nonresponders N=52

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Responders N=22

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Selected Important Safety Information

• Hyperglycemia has been observed. Monitor serum glucose, especially in diabetic or potentially diabetic patients. Adjustment of diet, therapy for increased glucose, or both may be necessary to prevent hyperglycemia.

Before prescribing ZOLINZA, please read the physician Prescribing Information. The Patient Product Information is also available.

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